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Literature summary for 3.4.21.89 extracted from

  • Harris, D.A.; Powers, M.E.; Romesberg, F.E.
    Synthesis and biological evaluation of penem inhibitors of bacterial signal peptidase (2009), Bioorg. Med. Chem. Lett., 19, 3787-3790.
    View publication on PubMed
Search for more literature for 3.4.21.89

Inhibitors

Inhibitors Comment Organism Structure
4-nitrobenzyl (5S,6S)-6-(1-hydroxyethyl)-7-oxo-4-thia-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylate
-
 Staphylococcus epidermidis RP62A
4-nitrobenzyl (5S,6S)-6-[(1R)-1-(acetyloxy)ethyl]-7-oxo-4-thia-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylate
-
 Staphylococcus epidermidis RP62A
4-nitrobenzyl (5S,6S)-6-[(1R)-1-(butanoyloxy)ethyl]-7-oxo-4-thia-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylate
-
 Staphylococcus epidermidis RP62A
4-nitrobenzyl (5S,6S)-6-[(1R)-1-(ethoxymethoxy)ethyl]-7-oxo-4-thia-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylate
-
 Staphylococcus epidermidis RP62A
4-nitrobenzyl (5S,6S)-6-[(1R)-1-(methoxymethoxy)ethyl]-7-oxo-4-thia-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylate
-
 Staphylococcus epidermidis RP62A
4-nitrobenzyl (5S,6S)-6-[(1R)-1-[(2-methylbutanoyl)oxy]ethyl]-7-oxo-4-thia-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylate
-
 Staphylococcus epidermidis RP62A
4-nitrobenzyl (5S,6S)-6-[(1R)-1-[(2-methylpropanoyl)oxy]ethyl]-7-oxo-4-thia-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylate
-
 Staphylococcus epidermidis RP62A
4-nitrobenzyl (5S,6S)-6-[(1R)-1-[(acetyloxy)methoxy]ethyl]-7-oxo-4-thia-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylate
-
 Staphylococcus epidermidis RP62A
4-nitrobenzyl (5S,6S)-6-[(1R)-1-[(ethylcarbamoyl)oxy]ethyl]-7-oxo-4-thia-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylate
-
 Staphylococcus epidermidis RP62A
4-nitrobenzyl (5S,6S)-6-[(1R)-1-[(N-acetylalanyl)oxy]ethyl]-7-oxo-4-thia-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylate
-
 Staphylococcus epidermidis RP62A
4-nitrobenzyl (5S,6S)-6-[(1R)-1-[(N-acetylglycyl)oxy]ethyl]-7-oxo-4-thia-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylate
-
 Staphylococcus epidermidis RP62A
4-nitrobenzyl (5S,6S)-6-[(1R)-1-[(N-acetylisoleucyl)oxy]ethyl]-7-oxo-4-thia-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylate
-
 Staphylococcus epidermidis RP62A
4-nitrobenzyl (5S,6S)-6-[(1R)-1-[(N-acetylvalyl)oxy]ethyl]-7-oxo-4-thia-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylate
-
 Staphylococcus epidermidis RP62A
4-nitrobenzyl (5S,6S)-7-oxo-6-[(1R)-1-(propanoyloxy)ethyl]-4-thia-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylate
-
 Staphylococcus epidermidis RP62A
4-nitrobenzyl (5S,6S)-7-oxo-6-[(1R)-1-[(propan-2-ylcarbamoyl)oxy]ethyl]-4-thia-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylate
-
 Staphylococcus epidermidis RP62A
additional information synthesis of a 5S penem from 6-aminopenicillanic acid, structure-activity relationships, overview Staphylococcus epidermidis RP62A

Organism

Organism UniProt Comment Textmining
Staphylococcus epidermidis RP62A
-
-
-

Synonyms

Synonyms Comment Organism
type I signal peptidase
-
 Staphylococcus epidermidis RP62A