Literature summary for 3.4.21.88 extracted from

Medina-Ruiz, L.; Campoy, S.; Latasa, C.; Cardenas, P.; Alonso, J.C.; Barbe, J.
Overexpression of the recA gene decreases oral but not intraperitoneal fitness of Salmonella enterica (2010), Infect. Immun., 78, 3217-3223.

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Protein Variants

Protein Variants	Comment	Organism
additional information	introduction of a mutation recAo6869 in the LexA binding site, in the promoter region of the recA gene, leads to dramatically decreased fitness of orally but not intraperitoneally inoculated recAo6869 cells. However, the SOS response of this mutant is induced normally, and there is no increase in the sensitivity of the strain toward DNA-damaging agents, bile salts, or alterations in pH. Nevertheless, recAo6869 cells are unable to swarm and their capacity to cross the intestinal epithelium is significantly reduced, phenotype, detailed overview. The rate of RecA protein accumulation increases about 5fold in mitomycin C-treated wild-type cells, whereas no induction is observed in the lexA3(Ind) strain	Salmonella enterica

Organism

Organism	UniProt	Comment	Textmining
Salmonella enterica	-	ATCC 14028, but recAo6869 Km	-
Salmonella enterica UA1876	-	ATCC 14028, but recAo6869 Km	-

Synonyms

Synonyms	Comment	Organism
LexA protein	-	Salmonella enterica

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Release 2023.1 (January 2023)