Activating Compound | Comment | Organism | Structure |
---|---|---|---|
additional information | glucocorticoid treatment markedly enhances granzyme A expression in glucocorticoid-sensitive but not in glucocorticoid-resistant cell lines | Homo sapiens |
Application | Comment | Organism |
---|---|---|
medicine | investigation of glucocorticoid-induced expression of granzyme A as a potential early biomarker for personalized therapy of acute lymphoblastic leukemia patients | Homo sapiens |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | P12544 | - |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
acute lymphoblastic leukemia cell line | acute lymphoblastic leukemia-derived cell line 697 used as a positive control, granzyme A mediated glucocorticoid-induced apoptosis shown | Homo sapiens | - |
Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
---|---|---|---|
additional information | - |
glucocorticoid sensitivity among cell lines derived from acute lymphoblastic leukemia patients analyzed, correlation between glucocorticoid-induced apoptosis and glucocorticoid-induced mRNA expression of granzyme A shown | Homo sapiens |
Synonyms | Comment | Organism |
---|---|---|
Gzma | - |
Homo sapiens |