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Literature summary for 3.4.21.7 extracted from

  • Buhl, K.; Friis, U.; Svenningsen, P.; Gulaveerasingam, A.; Ovesen, P.; Frederiksen-Moller, B.; Jespersen, B.; Bistrup, C.; Jensen, B.
    Urinary plasmin activates collecting duct ENaC current in preeclampsia (2012), Hypertension, 60, 1346-1351.
    View publication on PubMed

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
83000
-
x * 83000, SDS-PAGE Homo sapiens

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
epithelial sodium channel + H2O Homo sapiens
-
epithelial sodium channel gamma subunit + ?
-
?

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
urine
-
Homo sapiens
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
epithelial sodium channel + H2O
-
Homo sapiens epithelial sodium channel gamma subunit + ?
-
?

Subunits

Subunits Comment Organism
? x * 83000, SDS-PAGE Homo sapiens

General Information

General Information Comment Organism
physiological function proteolytic activation of ENaC by plasmin contributes to Na+ retention and hypertension in preeclampsia Homo sapiens