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BRENDA support

Literature summary for 3.4.21.7 extracted from

  • Sulniute, R.; Lindh, T.; Wilczynska, M.; Li, J.; Ny, T.
    Plasmin is essential in preventing periodontitis in mice (2011), Am. J. Pathol., 179, 819-828.
    View publication on PubMedView publication on EuropePMC

Organism

Organism UniProt Comment Textmining
Mus musculus
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-
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Source Tissue

Source Tissue Comment Organism Textmining
peridontium
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Mus musculus
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General Information

General Information Comment Organism
malfunction in plasminogen-deficient mice, periodontitis progresses rapidly, within 20 weeks. The plasminogen-deficient mice show detachment of gingival tissue, resorption of the cementum layer, formation of necrotic tissue, and severe alveolar bone degradation, phenotype, overview. Supplementation by injection of plasminogen-deficient mice with human plasminogen for 10 days leads to necrotic tissue absorption, inflammation subsidence, and full regeneration of gum tissues Mus musculus
physiological function plasmin is essential in preventing periodontitis in mice Mus musculus