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Literature summary for 3.4.21.7 extracted from
- Matrix metalloproteinase-1 activation via plasmin generated on alveolar epithelial cell surfaces (2006), Lung, 184, 15-19.
Application
| Application | Comment | Organism |
|---|---|---|
| medicine | plasmin generation system plays an important role in tissue repair/remodeling | Homo sapiens |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Homo sapiens | - |
- |
- |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| A-549 cell | plasmin is generated by the plasmin/u-PA system on surfaces of A-549 alveolar lining cells | Homo sapiens | - |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| pro-matrix metalloproteinase-1 + H2O | matrix metalloproteinase-1 activation by the UP A/plasmin system | Homo sapiens | active matrix metalloproteinase-1 | - |
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