Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
mitochondrion | - |
Saccharomyces cerevisiae | 5739 | - |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Saccharomyces cerevisiae | - |
- |
- |
General Information | Comment | Organism |
---|---|---|
physiological function | mitochondrial proteins aggregate to a substantial extent if they are challenged by either heat stress or reactive oxygen. As an important aspect of quality control, the proteolytic activity of Pim1 prevents the accumulation of these aggregation-prone polypeptides, resulting in prevention of proteotoxic effects | Saccharomyces cerevisiae |