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Literature summary for 3.4.21.53 extracted from

  • Liu, T.; Lu, B.; Lee, I.; Ondrovicova, G.; Kutejova, E.; Suzuki, C.K.
    DNA and RNA binding by the mitochondrial Lon protease is regulated by nucleotide and protein substrates (2004), J. Biol. Chem., 279, 13902-13910.
    View publication on PubMed
Search for more literature for 3.4.21.53

Inhibitors

Inhibitors Comment Organism Structure
ATP inhibits binding of enzyme to DNA or RNA Homo sapiens

Localization

Localization Comment Organism GeneOntology No. Textmining
mitochondrion
-
 Homo sapiens 5739
-

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
additional information Homo sapiens enzyme participates directly in the metabolism of mitochondrial DNA ?
-
 ?

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-
Homo sapiens
-
 human
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
additional information enzyme participates directly in the metabolism of mitochondrial DNA Homo sapiens ?
-
 ?

Subunits

Subunits Comment Organism
More enzyme binds GT-rich sequences found in the heavy strand of mitochondrial DNA and also interacts specifically with GU-rich RNA. Nucleotide inhibition and protein substrate stimulation coordinately regulate DNA binding Homo sapiens