Activating Compound | Comment | Organism | Structure |
---|---|---|---|
adenosine 5'-(3-thiotriphosphate) | i.e. adenosine 5'-O-(thiotriphosphate) or ATP-gamma-S, activation | Escherichia coli | |
adenosine 5'-(3-thiotriphosphate) | equally effective as ATP with casein as substrate | Escherichia coli | |
Adenosine 5'-(alpha-thio)triphosphate | activation, Rp-diastereoisomer stimulates peptide hydrolysis much more effectively than Sp-diastereoisomer | Escherichia coli | |
Adenyl-5'-yl imidodiphosphate | can replace ATP | Escherichia coli | |
Adenyl-5'-yl imidodiphosphate | i.e. AMP-PNP, activation | Escherichia coli | |
Adenyl-5'-yl imidodiphosphate | peptide hydrolysis | Escherichia coli | |
additional information | ATP cannot be replaced by adenosine 5'-(beta-thiotriphosphate) | Escherichia coli |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
Adenosine 5'-(betathio)triphosphate | - |
Escherichia coli | |
ADP | - |
Escherichia coli | |
Co2+ | - |
Escherichia coli |
Metals/Ions | Comment | Organism | Structure |
---|---|---|---|
Ca2+ | poor substitute for Mg2+ in ATP hydrolysis | Escherichia coli | |
Ca2+ | activation, as Ca2+-ATP | Escherichia coli | |
Ca2+ | slight | Escherichia coli | |
Mg2+ | requirement | Escherichia coli | |
additional information | Co2+ cannot replace Mg2+ | Escherichia coli |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Escherichia coli | - |
- |
- |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
casein + H2O | - |
Escherichia coli | hydrolyzed casein | - |
? | |
Succinyl-Phe-Ala-Phe-methoxynaphthylamide + H2O | - |
Escherichia coli | Succinyl-Phe-Ala-Phe + methoxynaphthylamine | - |
? |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
ATP | requirement | Escherichia coli | |
ATP | ATP-dependent protease | Escherichia coli |