Inhibitors | Comment | Organism | Structure |
---|---|---|---|
additional information | binding modes of a new class of orally available thrombin inhibitors based on 4-aminopyrimidine. Two inhibitors based on 4-aminopyridine bind in different ways. One forms a water-mediated hydrogen bond to the active site Ser195, the other induces a rotation of the Ser214-Trp215 peptide plane that is unprecedent in thrombin structures | Homo sapiens |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |