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Literature summary for 3.4.21.5 extracted from

  • Naski, M.C.; Lorand, L.; Shafer, J.A.
    Characterization of the kinetic pathway for fibrin promotion of alpha-thrombin-catalyzed activation of plasma factor XIII (1991), Biochemistry, 30, 934-941.
    View publication on PubMed

Inhibitors

Inhibitors Comment Organism Structure
additional information a 12-residue peptide, which binds to an exosite alpha-thrombin and blocks the interaction of alpha-thrombin with fibrinogen and fibrin, competitively inhibits alpha-thrombin-catalyzed release of both fibrinopeptide B and activation peptide from the fibrin I-plasma factor XIII complex Homo sapiens

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
fibrin I-plasma factor XIII complex + H2O
-
Homo sapiens activation peptide + fibrinopeptide B
-
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