General Stability | Organism |
---|---|
autolytic degradation during sedimentation in neutral salt solution | Homo sapiens |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
diisopropyl fluorophosphate | - |
Homo sapiens |
Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|
31500 | 40600 | thrombin in 0.21 M NaCl, 0.02 M sodium phosphate, pH 7.2, equilibrium sedimentation | Homo sapiens |
32000 | - |
1 * 4600, A chain, + 1 * 32000, B chain, reduced alpha-thrombin, SDS-PAGE | Homo sapiens |
36600 | - |
equilibrium sedimentation | Homo sapiens |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Posttranslational Modification | Comment | Organism |
---|---|---|
side-chain modification | carbohydrate is associated only with the B chain | Homo sapiens |
Storage Stability | Organism |
---|---|
-50°C, 0.75 M NaCl, pH 6, stable for about 1 year | Homo sapiens |
4°C, 0.75 M NaCl, pH 6, stable for about 1 week | Homo sapiens |
Subunits | Comment | Organism |
---|---|---|
dimer | 1 * 4600, A chain, + 1 * 32000, B chain, reduced alpha-thrombin, SDS-PAGE | Homo sapiens |
Temperature Stability Minimum [°C] | Temperature Stability Maximum [°C] | Comment | Organism |
---|---|---|---|
23 | - |
stable for up to 3 days at room temperature | Homo sapiens |
35 | - |
pH 6, loss of activity above | Homo sapiens |
pH Stability | pH Stability Maximum | Comment | Organism |
---|---|---|---|
5 | 10.3 | rapid loss of clotting and esterase activity below pH 5 and above pH 10.3 | Homo sapiens |