KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
0.000178 | - |
thrombin-activatable fibrinolysis inhibitor | presence of thrombomodulin, Km(app) value | Homo sapiens |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
additional information | protein context, as well as the identity of amino acids at protease cleavage sites, dictate protease specificity | Homo sapiens | ? | - |
? | |
thrombin-activatable fibrinolysis inhibitor + H2O | mutant variants with variants in the amino acids surrounding the scissile R92-A93 bond such as P91S, R92K, and S90P exhibit specific impairment of activation by thrombin or thrombin/thrombomodulin | Homo sapiens | ? | - |
? |
Turnover Number Minimum [1/s] | Turnover Number Maximum [1/s] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
0.315 | - |
thrombin-activatable fibrinolysis inhibitor | presence of thrombomodulin, kcat(app) value | Homo sapiens |