Crystallization (Comment) | Organism |
---|---|
mutant E217K, shows repositioned E192 and destructed oxyanion hole | Homo sapiens |
Protein Variants | Comment | Organism |
---|---|---|
E217K | retains ability to activate the anticoagulant protein C pathway, inable to convert fibrinogen to a fibrin clot. Allosteric inactivation by destabilization of Na+ binding site, thus representing the Na+-free, catalytically slow form | Homo sapiens |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | P00734 | - |
- |