Inhibitors | Comment | Organism | Structure |
---|---|---|---|
Ca2+ | slight inhibition at 10 mM | Homo sapiens | |
Ca2+ | 50% inhibition at 10 mM | Salmo salar |
Metals/Ions | Comment | Organism | Structure |
---|---|---|---|
additional information | not affected by NaCl up to 600 mM | Homo sapiens | |
NaCl | 50% activation at 600 mM | Salmo salar |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
additional information | Homo sapiens | enzyme stimulates platelets and exposure of phosphatidylserine on the external surface | ? | - |
? | |
additional information | Salmo salar | enzyme stimulates platelets and exposure of phosphatidylserine on the external surface | ? | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Salmo salar | - |
salmon | - |
Posttranslational Modification | Comment | Organism |
---|---|---|
proteolytic modification | activation of prothrombin by snake venom from Oxyuranus scutellatus | Salmo salar |
Purification (Comment) | Organism |
---|---|
from plasma, to homogeneity | Salmo salar |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
plasma | - |
Salmo salar | - |
Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
---|---|---|---|
additional information | - |
- |
Salmo salar |
Storage Stability | Organism |
---|---|
0°C, on ice, 8 h, stable | Salmo salar |
22°C, at room temperature, several hours, stable, lyophilized stable for several months | Salmo salar |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
fibrinogen + H2O | from human and salmon | Salmo salar | fibrin + fibrinopeptide A + fibrinopeptide B | - |
? | |
additional information | enzyme stimulates platelets and exposure of phosphatidylserine on the external surface | Homo sapiens | ? | - |
? | |
additional information | enzyme stimulates platelets and exposure of phosphatidylserine on the external surface | Salmo salar | ? | - |
? | |
tosyl-Gly-Pro-Arg-4-nitroanilide + H2O | - |
Homo sapiens | tosyl-Gly-Pro-Arg + 4-nitroaniline | - |
? | |
tosyl-Gly-Pro-Arg-4-nitroanilide + H2O | - |
Salmo salar | tosyl-Gly-Pro-Arg + 4-nitroaniline | - |
? |
Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
---|---|---|---|
30 | - |
- |
Salmo salar |
35 | - |
- |
Homo sapiens |
Temperature Stability Minimum [°C] | Temperature Stability Maximum [°C] | Comment | Organism |
---|---|---|---|
80 | - |
lyophilized enzyme, 8 h, 90% remaining activity | Homo sapiens |
80 | - |
lyophilized purified enzyme, 8 h, 80% remaining activity | Salmo salar |
pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
---|---|---|---|
8 | - |
- |
Homo sapiens |
8.5 | - |
- |
Salmo salar |