Literature summary for 3.4.21.4 extracted from

Bhagwat, S.S.; Larsen, A.K.; Winberg, J.O.; Seternes, O.M.; Bang, B.E.
Salmon and king crab trypsin stimulate interleukin-8 and matrix metalloproteinases via protease-activated receptor-2 in the skin keratinocytic HaCaT cell line (2014), Food Chem. Toxicol., 69, 303-311.

Search for more literature for 3.4.21.4

Application

Application	Comment	Organism
medicine	role of trypsin as inducer of inflammation in skin via secretion of inflammatory mediators. King crab trypsin enhances the secretion ofIL-8, MMP-2 and MMP-9 by human skin keratinocytes. Exposure to proteases from the seafood may lead to inflammatory reactions in skin	Paralithodes camtschaticus
medicine	role of trypsin as inducer of inflammation in skin via secretion of inflammatory mediators. Salmon trypsin enhances the secretion of IL-8 and MMP-2 by human skin keratinocytes. Exposure to proteases from the seafood may lead to inflammatory reactions in skin	Salmo salar

Organism

Organism	UniProt	Comment	Textmining
Paralithodes camtschaticus	Q8WR10	-	-
Salmo salar	-	-	-

Source Tissue

Source Tissue	Comment	Organism	Textmining

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Release 2023.1 (January 2023)