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Literature summary for 3.4.21.4 extracted from

  • Larsen, A.K.; Seternes, O.M.; Larsen, M.; Aasmoe, L.; Bang, B.
    Salmon trypsin stimulates the expression of interleukin-8 via protease-activated receptor-2 (2008), Toxicol. Appl. Pharmacol., 230, 276-282.
    View publication on PubMed

Inhibitors

Inhibitors Comment Organism Structure
Aprotinin
-
Salmo salar
Protease Inhibitor Cocktail
-
Salmo salar

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
additional information Salmo salar salmon trypsin induces interleukin-8 production in human airway epithelial cells, purified salmon trypsin activates nuclear factor-kappa B-mediated gene expression in HeLa cells overexpressing human protease-activated receptor-2, the production of interleukin-8 by salmon trypsin is mediated by protease-activated receptor-2 ?
-
?

Organism

Organism UniProt Comment Textmining
Salmo salar
-
-
-

Purification (Commentary)

Purification (Comment) Organism
-
Salmo salar

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
additional information salmon trypsin induces interleukin-8 production in human airway epithelial cells, purified salmon trypsin activates nuclear factor-kappa B-mediated gene expression in HeLa cells overexpressing human protease-activated receptor-2, the production of interleukin-8 by salmon trypsin is mediated by protease-activated receptor-2 Salmo salar ?
-
?
N-alpha-benzoyl-DL-Arg-4-nitroanilide + H2O
-
Salmo salar N-alpha-benzoyl-DL-Arg + 4-nitroaniline
-
?