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Literature summary for 3.4.21.4 extracted from

  • Szepessy, E.; Sahin-Toth, M.
    Human mesotrypsin exhibits restricted S1 subsite specificity with a strong preference for small polar side chains (2006), FEBS J., 273, 2942-2954.
    View publication on PubMedView publication on EuropePMC

Inhibitors

Inhibitors Comment Organism Structure
alpha1-antitrypsin Pittsburgh effective inhibitor, variant of alpha1-antitrypsin containing an Arg residue in place of the P1 Met358 in the reactive-site peptide bond Homo sapiens
additional information mesotrypsin exhibits complete resistance against wild-type alpha1-antitrypsin Homo sapiens

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
Gly-Pro-Arg-p-nitroanilide + H2O
-
Homo sapiens Gly-Pro-Arg + p-nitroaniline
-
?
additional information exhibits a relatively high specificity for Lys/Arg-Ser/Thr peptide bonds Homo sapiens ?
-
?

Synonyms

Synonyms Comment Organism
mesotrypsin
-
Homo sapiens