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Literature summary for 3.4.21.107 extracted from

  • Chien, J.; Ota, T.; Aletti, G.; Shridhar, R.; Boccellino, M.; Quagliuolo, L.; Baldi, A.; Shridhar, V.
    Serine protease HtrA1 associates with microtubules and inhibits cell migration (2009), Mol. Cell. Biol., 29, 4177-4187.
    View publication on PubMedView publication on EuropePMC
Search for more literature for 3.4.21.107

Localization

Localization Comment Organism GeneOntology No. Textmining
centrosome intracellular HtrA1 associates with centrosomes Homo sapiens 5813
-
microtubule intracellular HtrA1 associates with newly polymerized microtubules Homo sapiens 5874
-

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
alpha-tubulin + H2O Homo sapiens
-
 ?
-
 ?
beta-tubulin + H2O Homo sapiens
-
 ?
-
 ?

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
A-2780 cell
-
 Homo sapiens
-
HeLa cell
-
 Homo sapiens
-
OV-202 cell
-
 Homo sapiens
-
SKOV-3 cell
-
 Homo sapiens
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
alpha-tubulin + H2O
-
 Homo sapiens ?
-
 ?
beta-tubulin + H2O
-
 Homo sapiens ?
-
 ?

Synonyms

Synonyms Comment Organism
DegP
-
 Homo sapiens
high temperature requirement A1
-
 Homo sapiens
HtrA1
-
 Homo sapiens

General Information

General Information Comment Organism
physiological function HtrA1 modulates microtubule stability and cell motility. In vitro, purified HtrA1 promotes microtubule assembly Homo sapiens