Literature summary for 3.4.21.102 extracted from

Bandara, A.B.; Sriranganathan, N.; Schurig, G.G.; Boyle, S.M.
Carboxyl-terminal protease regulates Brucella suis morphology in culture and persistence in macrophages and mice (2005), J. Bacteriol., 187, 5767-5775.

Search for more literature for 3.4.21.102

Cloned(Commentary)

Cloned (Comment)	Organism
gene ctpA, DNA and amino acid sequence determination and analysis, genomic organization and structure, complementation of the mutant strain 1330DELTActpa by expression of wild-type gene ctpA	Brucella suis bv. 1

Protein Variants

Protein Variants	Comment	Organism
additional information	the enzyme-deficient strain 1330DELTActpa is generated by allelic exchange, the mutant produces smaller colonies on enriched agar plates and exhibits a 50% decrease in growth rate in enriched liquid medium and no growth in salt-free enriched medium, the mutant cells show a spherical shape, increased cell diameter, and membranes partially dissociated from the cell envelope compared to the wild-type cells, smooth phenotype, overview, the virulence of the wild-type strain 1330 is reduced by the mutant strain 1330DELTAcptA in murine spleen, overview	Brucella suis bv. 1

Localization

Localization	Comment	Organism	GeneOntology No.	Textmining
periplasm	-	Brucella suis bv. 1	-	-

Molecular Weight [Da]

Molecular Weight [Da]	Molecular Weight Maximum [Da]	Comment	Organism
42500	-	x * 42500, about, sequence calculation	Brucella suis bv. 1

Natural Substrates/ Products (Substrates)

Natural Substrates	Organism	Comment (Nat. Sub.)	Natural Products	Comment (Nat. Pro.)	Rev.	Reac.
additional information	Brucella suis bv. 1	the enzyme belongs to the family of endoproteases involved in the maturation of proteins destined for the cell envelope	?	-	?

Organism

Organism	UniProt	Comment	Textmining
Brucella suis bv. 1	A0A0H3G8P9	gene ctpA	-

Source Tissue

Source Tissue	Comment	Organism	Textmining

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
additional information	the enzyme belongs to the family of endoproteases involved in the maturation of proteins destined for the cell envelope	Brucella suis bv. 1	?	-	?

Subunits

Subunits	Comment	Organism
?	x * 42500, about, sequence calculation	Brucella suis bv. 1

Synonyms

Synonyms	Comment	Organism
carboxyl-terminal processing protease	-	Brucella suis bv. 1
carboxyl-terminal protease	-	Brucella suis bv. 1
CtpA	-	Brucella suis bv. 1

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Release 2023.1 (January 2023)