Literature summary for 3.4.21.1 extracted from

Spink, E.; Cosgrove, S.; Rogers, L.; Hewage, C.; Malthouse, J.P.
13C and 1H NMR studies of ionizations and hydrogen bonding in chymotrypsin-glyoxal inhibitor complexes (2007), J. Biol. Chem., 282, 7852-7861.

Search for more literature for 3.4.21.1

Inhibitors

Inhibitors	Comment	Organism	Structure
benzyloxycarbonyl-Ala-Ala-Phe-glyoxal	-	Bos taurus
benzyloxycarbonyl-Ala-Pro-Phe-glyoxal	-	Bos taurus

Organism

Organism	UniProt	Comment	Textmining
Bos taurus	-	-	-

Source Tissue

Source Tissue	Comment	Organism	Textmining
pancreas	-	Bos taurus	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
N-succinyl-Ala-Ala-Pro-Phe-p-nitroanilide + H2O	-	Bos taurus	N-succinyl-Ala-Ala-Pro-Phe + p-nitroaniline	-	?

Synonyms

Synonyms	Comment	Organism
alpha-chymotrypsin	-	Bos taurus

Ki Value [mM]

Ki Value [mM]	Ki Value maximum [mM]	Inhibitor	Comment	Organism	Structure
0.019	-	benzyloxycarbonyl-Ala-Pro-Phe-glyoxal	at pH 7.23 and 25°C	Bos taurus
0.024	-	benzyloxycarbonyl-Ala-Pro-Phe-glyoxal	at pH 7.17 and 25°C	Bos taurus
0.344	-	benzyloxycarbonyl-Ala-Ala-Phe-glyoxal	at 25°C	Bos taurus

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Release 2023.1 (January 2023)