Literature summary for 3.4.17.1 extracted from

Arolas, J.L.; Popowicz, G.M.; Lorenzo, J.; Sommerhoff, C.P.; Huber, R.; Aviles, F.X.; Holak, T.A.
The three-dimensional structures of tick carboxypeptidase inhibitor in complex with A/B carboxypeptidases reveal a novel double-headed binding mode (2005), J. Mol. Biol., 350, 489-498.

Search for more literature for 3.4.17.1

Application

Application	Comment	Organism
drug development	the enzyme is a target for drug development for biotechnological and biomedical applications	Bos taurus

Crystallization (Commentary)

Crystallization (Comment)	Organism
purified enzyme in complex with the tick carboxypeptidase inhibitor, X-ray diffraction structure determination and analysis at 1.7 A resolution, comparison to the structure of unligated enzyme PDB code 1M4L, overview	Bos taurus

Inhibitors

Inhibitors	Comment	Organism	Structure
tick carboxypeptidase inhibitor	i.e. TCI, a 75 amino acid, two-domain protein from the blood-sucking tick Rhipcephalus bursa, recombinantly expressed in Escherichia coli and purified, three-dimensional structure of the enzyme-inhibitor protein complex, inhibitor binding and inhibition mechanism, overview	Bos taurus

Organism

Organism	UniProt	Comment	Textmining
Bos taurus	P00730	-	-

Synonyms

Synonyms	Comment	Organism
CPA	-	Bos taurus

Use of this online version of BRENDA is free under the CC BY 4.0 license. See terms of use for full details.

Release 2023.1 (January 2023)