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Literature summary for 3.4.16.4 extracted from

  • Adediran, S.A.; Cabaret, D.; Flavell, R.R.; Sammons, J.A.; Wakselman, M.; Pratt, R.F.
    Synthesis and beta-lactamase reactivity of alpha -substituted phenaceturates (2006), Bioorg. Med. Chem., 14, 7023-7033.
    View publication on PubMed
Search for more literature for 3.4.16.4

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
0.2
-
 3-carboxyphenyl N-(phenylacetyl)-alpha-methoxyglycinate
-
 Neisseria gonorrhoeae
0.2
-
 3-carboxyphenyl N-(phenylacetyl)-alpha-methoxyglycinate
-
 Actinomadura sp. R39
0.35
-
 3-carboxyphenyl N-(phenylacetyl)-alpha-serinate
-
 Streptomyces sp. R61
0.45
-
 3-carboxyphenyl N-(phenylacetyl)-alpha-methoxyglycinate
-
 Streptomyces sp. R61
0.85
-
 3-carboxyphenyl N-(phenylacetyl)-alpha-serinate
-
 Actinomadura sp. R39
1.8
-
 3-carboxyphenyl N-(phenylacetyl)-alpha-serinate
-
 Neisseria gonorrhoeae

Organism

Organism UniProt Comment Textmining
Actinomadura sp. R39
-
-
-
Neisseria gonorrhoeae
-
-
-
Streptomyces sp. R61
-
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3-carboxyphenyl N-(phenylacetyl)-alpha-methoxyglycinate + H2O
-
 Neisseria gonorrhoeae ?
-
 ?
3-carboxyphenyl N-(phenylacetyl)-alpha-methoxyglycinate + H2O
-
 Streptomyces sp. R61 ?
-
 ?
3-carboxyphenyl N-(phenylacetyl)-alpha-methoxyglycinate + H2O
-
 Actinomadura sp. R39 ?
-
 ?
3-carboxyphenyl N-(phenylacetyl)-alpha-serinate + H2O
-
 Neisseria gonorrhoeae ?
-
 ?
3-carboxyphenyl N-(phenylacetyl)-alpha-serinate + H2O
-
 Streptomyces sp. R61 ?
-
 ?
3-carboxyphenyl N-(phenylacetyl)-alpha-serinate + H2O
-
 Actinomadura sp. R39 ?
-
 ?

Synonyms

Synonyms Comment Organism
DD-peptidase
-
 Neisseria gonorrhoeae
DD-peptidase
-
 Streptomyces sp. R61
DD-peptidase
-
 Actinomadura sp. R39
PBP3
-
 Neisseria gonorrhoeae

Temperature Optimum [°C]

Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
37
-
 kinetic assay Neisseria gonorrhoeae
37
-
 kinetic assay Streptomyces sp. R61
37
-
 kinetic assay Actinomadura sp. R39

Turnover Number [1/s]

Turnover Number Minimum [1/s] Turnover Number Maximum [1/s] Substrate Comment Organism Structure
0.65
-
 3-carboxyphenyl N-(phenylacetyl)-alpha-serinate
-
 Actinomadura sp. R39
2.2
-
 3-carboxyphenyl N-(phenylacetyl)-alpha-serinate
-
 Streptomyces sp. R61
22
-
 3-carboxyphenyl N-(phenylacetyl)-alpha-serinate
-
 Neisseria gonorrhoeae
44
-
 3-carboxyphenyl N-(phenylacetyl)-alpha-methoxyglycinate
-
 Streptomyces sp. R61
106
-
 3-carboxyphenyl N-(phenylacetyl)-alpha-methoxyglycinate
-
 Neisseria gonorrhoeae
114
-
 3-carboxyphenyl N-(phenylacetyl)-alpha-methoxyglycinate
-
 Actinomadura sp. R39

pH Optimum

pH Optimum Minimum pH Optimum Maximum Comment Organism
7.5
-
 kinetic assay Streptomyces sp. R61
7.7
-
 kinetic assay Actinomadura sp. R39
8.5
-
 kinetic assay Neisseria gonorrhoeae