Inhibitors | Comment | Organism | Structure |
---|---|---|---|
betulinic acid | i.e. 3beta-hdroxy-lup-20(29)-en-28-oic acid, inhibits the enzyme and is involved in anti-angiogenesis due to further inhibition of expression and decrease in expressions of alpha1 and alpha2 integrins, hypoxia-inducible factor 1, HIF-1, and vascular endothelial cell growth factor, detailed overview | Homo sapiens |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
uterine adenocarcinoma cell | Ishikawa cell line | Homo sapiens | - |
General Information | Comment | Organism |
---|---|---|
malfunction | prolidase may play a role in angiogenesis | Homo sapiens |
metabolism | prolidase catalyzes the final step of collagen degradation | Homo sapiens |