Activating Compound | Comment | Organism | Structure |
---|---|---|---|
8-Br-cGMP | strong and rapid stimulation of enzyme activity by phosphorylation | Mus musculus | |
NO | NO-donors such as SIN I and DETA/NO increase enzyme activity in time- and dose-dependent manner. Enzyme activity also increases upon transfection of cells with iNOS. Increased enzymic activity is accompanied by increase in serine/threonine phosphorylation of enzyme | Mus musculus |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Mus musculus | - |
- |
- |
Posttranslational Modification | Comment | Organism |
---|---|---|
phosphoprotein | increased enzymic activity after treatment with NO donors is accompanied by increase in serine/threonine phosphorylation of enzyme. 8-Br-cGMP strongly and rapidly stimulates enzyme activity by phosphorylation | Mus musculus |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
NIH-3T3 cell | fibroblast cell line | Mus musculus | - |