Literature summary for 3.4.13.9 extracted from

Brown, P.; O'Cuinn, G.
The purification and characterization of a proline dipeptidase from guinea pig brain (1983), J. Biol. Chem., 258, 6147-6154.

Search for more literature for 3.4.13.9

Inhibitors

Inhibitors	Comment	Organism	Structure
1,10-phenanthroline	-	Cavia porcellus
Cu2+	-	Cavia porcellus
Hg2+	-	Cavia porcellus
Zn2+	slightly	Cavia porcellus

Molecular Weight [Da]

Molecular Weight [Da]	Molecular Weight Maximum [Da]	Comment	Organism
64000	-	1 * 64000 + 1 * 68000, SDS-PAGE	Cavia porcellus
68000	-	1 * 64000 + 1 * 68000, SDS-PAGE	Cavia porcellus
132000	-	gradient gel electrophoresis	Cavia porcellus

Organism

Organism	UniProt	Comment	Textmining
Cavia porcellus	-	-	-

Source Tissue

Source Tissue	Comment	Organism	Textmining
brain	-	Cavia porcellus	-

Specific Activity [micromol/min/mg]

Specific Activity Minimum [µmol/min/mg]	Specific Activity Maximum [µmol/min/mg]	Comment	Organism
49.47	-	-	Cavia porcellus

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
Ile-Pro + H2O	-	Cavia porcellus	Ile + Pro	-	?
L-Leu-L-Pro + H2O	-	Cavia porcellus	L-Leu + L-Pro	-	?
L-Met-L-Pro + H2O	-	Cavia porcellus	L-Met + L-Pro	-	?

Subunits

Subunits	Comment	Organism
dimer	1 * 64000 + 1 * 68000, SDS-PAGE	Cavia porcellus

Turnover Number [1/s]

Turnover Number Minimum [1/s]	Turnover Number Maximum [1/s]	Substrate	Comment	Organism	Structure
additional information	-	additional information	-	Cavia porcellus
55.3	-	Ile-Pro	-	Cavia porcellus
111	-	L-Leu-L-Pro	-	Cavia porcellus
115	-	L-Met-L-Pro	-	Cavia porcellus

pH Optimum

pH Optimum Minimum	pH Optimum Maximum	Comment	Organism
7.5	-	-	Cavia porcellus

pH Range

pH Minimum	pH Maximum	Comment	Organism
5.5	8.6	less than 10% activity below and above	Cavia porcellus

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Release 2023.1 (January 2023)