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Literature summary for 3.4.11.3 extracted from
- Oxytocinase in the female rat hypothalamus: a novel mechanism controlling oxytocin neurones during lactation (2014), J. Neuroendocrinol., 26, 205-216.
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| amastatin | - |
Rattus norvegicus |  |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Rattus norvegicus | P97629 | - |
- |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| hypothalamus | - |
Rattus norvegicus | - |
| neuron | expressed in magnocellular neurones of the supraoptic (SON) and paraventricular (PVN) nuclei | Rattus norvegicus | - |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| oxytocinase | - |
Rattus norvegicus |
| P-LAP | - |
Rattus norvegicus |
| Placental leucine aminopeptidase | - |
Rattus norvegicus |
Expression
| Organism | Comment | Expression |
|---|---|---|
| Rattus norvegicus | expression is higher in lactating rats | up |
General Information
| General Information | Comment | Organism |
|---|---|---|
| malfunction | inhibition of central enzyme activity by injection of amastatin in anaesthetised suckling mothers increases the frequency of reflex milk ejections | Rattus norvegicus |
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Release 2023.1 (January 2023)
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