Activating Compound | Comment | Organism | Structure |
---|---|---|---|
additional information | 4fold up-regulation in case of oxygen or phosphorus deficit, but not in case of nitrogen or carbon deficit | Escherichia coli |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
dipeptides | inhibit the enzyme at high concentration in the medium | Lactococcus lactis | |
additional information | detection of en endogenous inhibior | Escherichia coli |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
cytosol | the enzyme is associated to the plasmam membrane at the cytosolic side | Pseudomonas aeruginosa | 5829 | - |
intracellular | - |
Pseudomonas fluorescens | 5622 | - |
plasma membrane | the enzyme is associated to the plasmam membrane at the cytosolic side | Pseudomonas aeruginosa | 5886 | - |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
additional information | Escherichia coli | aminopeptidase regulation mechanisms and biological functions, overview | ? | - |
? | |
additional information | Pseudomonas aeruginosa | aminopeptidase regulation mechanisms and biological functions, overview | ? | - |
? | |
additional information | Lactococcus lactis | aminopeptidase regulation mechanisms and biological functions, overview | ? | - |
? | |
additional information | Streptococcus thermophilus | aminopeptidase regulation mechanisms and biological functions, overview | ? | - |
? | |
additional information | Lactobacillus delbrueckii | aminopeptidase regulation mechanisms and biological functions, overview | ? | - |
? | |
additional information | Latilactobacillus curvatus | aminopeptidase regulation mechanisms and biological functions, overview | ? | - |
? | |
additional information | Pseudomonas fluorescens | the enzyme is involved in the transport and degradation of extracellular peptides, aminopeptidase regulation mechanisms and biological functions, overview | ? | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Escherichia coli | - |
- |
- |
Lactobacillus delbrueckii | - |
- |
- |
Lactococcus lactis | - |
- |
- |
Latilactobacillus curvatus | - |
- |
- |
Pseudomonas aeruginosa | - |
- |
- |
Pseudomonas fluorescens | - |
strain ATCC 948 | - |
Streptococcus thermophilus | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
additional information | enzyme expression during whole life cycle, 4fold up-regulation in case of oxygen or phosphorus deficit, but not in case of nitrogen or carbon deficit | Escherichia coli | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
additional information | aminopeptidase regulation mechanisms and biological functions, overview | Escherichia coli | ? | - |
? | |
additional information | aminopeptidase regulation mechanisms and biological functions, overview | Pseudomonas aeruginosa | ? | - |
? | |
additional information | aminopeptidase regulation mechanisms and biological functions, overview | Lactococcus lactis | ? | - |
? | |
additional information | aminopeptidase regulation mechanisms and biological functions, overview | Streptococcus thermophilus | ? | - |
? | |
additional information | aminopeptidase regulation mechanisms and biological functions, overview | Lactobacillus delbrueckii | ? | - |
? | |
additional information | aminopeptidase regulation mechanisms and biological functions, overview | Latilactobacillus curvatus | ? | - |
? | |
additional information | the enzyme is involved in the transport and degradation of extracellular peptides, aminopeptidase regulation mechanisms and biological functions, overview | Pseudomonas fluorescens | ? | - |
? | |
additional information | broad substrate specificity, the enzyme prefers N-terminal alkaline and aliphatic amino acid substrates showing high activity with peptides possessing N-terminal Lys or Leu residues and, to a lesser extent, Ala residues | Lactococcus lactis | ? | - |
? | |
additional information | broad substrate specificity, the enzyme prefers N-terminal alkaline and aliphatic amino acid substrates showing high activity with peptides possessing N-terminal Lys or Leu residues and, to a lesser extent, Ala residues | Streptococcus thermophilus | ? | - |
? | |
additional information | broad substrate specificity, the enzyme prefers N-terminal alkaline and aliphatic amino acid substrates showing high activity with peptides possessing N-terminal Lys or Leu residues and, to a lesser extent, Ala residues | Lactobacillus delbrueckii | ? | - |
? | |
additional information | broad substrate specificity, the enzyme prefers N-terminal alkaline and aliphatic amino acid substrates showing high activity with peptides possessing N-terminal Lys or Leu residues and, to a lesser extent, Ala residues | Latilactobacillus curvatus | ? | - |
? | |
additional information | the enzyme prefers N-terminal alkaline and aliphatic amino acid substrates showing high activity with peptides possessing N-terminal Ala, Arg, Lys or Leu residues | Pseudomonas fluorescens | ? | - |
? | |
additional information | the enzyme prefers N-terminal alkaline and aliphatic amino acid substrates showing high activity with peptides possessing N-terminal Ala, Arg, Lys or Leu residues | Pseudomonas aeruginosa | ? | - |
? |
Subunits | Comment | Organism |
---|---|---|
monomer | - |
Escherichia coli |
monomer | - |
Pseudomonas fluorescens |
monomer | - |
Pseudomonas aeruginosa |
monomer | - |
Lactococcus lactis |
monomer | - |
Streptococcus thermophilus |
monomer | - |
Lactobacillus delbrueckii |
monomer | - |
Latilactobacillus curvatus |
Synonyms | Comment | Organism |
---|---|---|
aminopeptidase N | - |
Escherichia coli |
aminopeptidase N | - |
Pseudomonas fluorescens |
aminopeptidase N | - |
Pseudomonas aeruginosa |
aminopeptidase N | - |
Lactococcus lactis |
aminopeptidase N | - |
Streptococcus thermophilus |
aminopeptidase N | - |
Lactobacillus delbrueckii |
aminopeptidase N | - |
Latilactobacillus curvatus |