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Literature summary for 3.4.11.18 extracted from

  • Haldar, M.K.; Scott, M.D.; Sule, N.; Srivastava, D.K.; Mallik, S.
    Synthesis of barbiturate-based methionine aminopeptidase-1 inhibitors (2008), Bioorg. Med. Chem. Lett., 18, 2373-2376.
    View publication on PubMedView publication on EuropePMC
Search for more literature for 3.4.11.18

Cloned(Commentary)

Cloned (Comment) Organism
-
 Homo sapiens

Inhibitors

Inhibitors Comment Organism Structure
5-[(2E)-hepta-2,6-dien-4-yn-1-ylidene]pyrimidine-2,4,6(1H,3H,5H)-trione
-
 Homo sapiens

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
Met-peptide + H2O Homo sapiens
-
 Met + peptide
-
 ?

Organism

Organism UniProt Comment Textmining
Homo sapiens P53582
-
-

Purification (Commentary)

Purification (Comment) Organism
-
 Homo sapiens

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
Met-peptide + H2O
-
 Homo sapiens Met + peptide
-
 ?

Synonyms

Synonyms Comment Organism
MetAP-1
-
 Homo sapiens
methionine aminopeptidase-1
-
 Homo sapiens

Ki Value [mM]

Ki Value [mM] Ki Value maximum [mM] Inhibitor Comment Organism Structure
0.162
-
 5-[(2E)-hepta-2,6-dien-4-yn-1-ylidene]pyrimidine-2,4,6(1H,3H,5H)-trione
-
 Homo sapiens