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Literature summary for 3.4.11.18 extracted from

  • Vetro, J.A.; Dummitt, B.; Micka, W.S.; Chang, Y.H.
    Evidence of a dominant negative mutant of yeast methionine aminopeptidase type 2 in Saccharomyces cerevisiae (2005), J. Cell. Biochem., 94, 656-668.
    View publication on PubMed

Protein Variants

Protein Variants Comment Organism
H174A no enzymic activity, overexpression using a strong promoter in map1 null strain is lethal, overexpression using a weak promoter slightly inhibits growth Saccharomyces cerevisiae
additional information enzyme deletion mutant, N-terminal region (residues 2-57) is essential but not sufficient for enzyme to fully interfere with map1 null growth Saccharomyces cerevisiae

Organism

Organism UniProt Comment Textmining
Saccharomyces cerevisiae
-
isoform Map2
-