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Literature summary for 3.4.11.18 extracted from
- Methionine aminopeptidase 2 inhibition is an effective treatment strategy for neuroblastoma in preclinical models (2005), Clin. Cancer Res., 11, 2680-2685.
Application
| Application | Comment | Organism |
|---|---|---|
| medicine | inhibitor A357300 in combination with cyclophosphamide sustains tumor regression and inhibits establishment and growth rate of hematogenous metastatic deposits following tail vein inocculation in CHP-134 neuroblastoma cells | Homo sapiens |
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| A-357300 | reversible | Homo sapiens |  |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Homo sapiens | - |
patient with high-risk neuroblastoma | - |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| CHP-134 cell | cell line derived from a patient with high-risk neuroblastoma | Homo sapiens | - |
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