Application | Comment | Organism |
---|---|---|
medicine | the modification of the active site residue His79 by the inhibitors fumagillin and ovalicin may prevent the action of the enzyme on proteins or peptides involved in angiogenesis. These compounds may be effective pharmacological agents against pathogenic and resistant forms of Escherichia coli and other microorganisms | Escherichia coli |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
fumagillin | fumagillin covalently modifies a conserved active-site histidine in the Escherichia coli methionine aminopeptidase | Escherichia coli | |
ovalicin | covalently modifies a conserved active-site histidine in the Escherichia coli methionine aminopeptidase | Escherichia coli |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Escherichia coli | - |
- |
- |