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Literature summary for 3.4.11.1 extracted from

  • Ledeme, N.; Hennon, G.; Vincent-Fiquet, O.; Plaquet, R.
    Purification and enzymatic properties of an L-leucine aminopeptidase from swine liver (1981), Biochim. Biophys. Acta, 660, 262-270.
    View publication on PubMed
Search for more literature for 3.4.11.1

Inhibitors

Inhibitors Comment Organism Structure
Citric acid
-
 Sus scrofa
Dodecylamino aliphatic alcohols
-
 Sus scrofa
Isocaproic acid
-
 Sus scrofa
p-chloromercuribenzoate
-
 Sus scrofa
Zn2+
-
 Sus scrofa

Localization

Localization Comment Organism GeneOntology No. Textmining
cytoplasm
-
 Sus scrofa 5737
-

Metals/Ions

Metals/Ions Comment Organism Structure
Mg2+ activation Sus scrofa
Mn2+ activation Sus scrofa
Zn2+ 4-6 gatom per mol Sus scrofa
Zn2+ 11.4 gatom per mol Sus scrofa

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
268000 270000 gel filtration Sus scrofa

Organism

Organism UniProt Comment Textmining
Sus scrofa
-
 hog
-

Purification (Commentary)

Purification (Comment) Organism
-
 Sus scrofa

Source Tissue

Source Tissue Comment Organism Textmining

Specific Activity [micromol/min/mg]

Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
additional information
-
-
 Sus scrofa

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
amino acid amides + H2O slow hydrolysis: Tyr, Phe Sus scrofa amino acid + NH3
-
 ?
amino acid amides + H2O fast hydrolysis: L-Leu Sus scrofa amino acid + NH3
-
 ?
L-amino acid-peptide + H2O Leu-Gly-Gly Sus scrofa amino acid + peptide
-
 ?

pH Optimum

pH Optimum Minimum pH Optimum Maximum Comment Organism
10
-
-
 Sus scrofa

pH Range

pH Minimum pH Maximum Comment Organism
7
-
 no activity below Sus scrofa