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Literature summary for 3.4.11.1 extracted from
- Identification of an intracellular M17 family leucine aminopeptidase that is required for virulence in Staphylococcus aureus (2012), Microbes Infect., 14, 989-999.
Localization
| Localization | Comment | Organism | GeneOntology No. | Textmining |
|---|---|---|---|---|
| intracellular | - |
Staphylococcus aureus | 5622 | - |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Staphylococcus aureus | - |
- |
- |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| LAP | - |
Staphylococcus aureus |
| pepZ | - |
Staphylococcus aureus |
Expression
| Organism | Comment | Expression |
|---|---|---|
| Staphylococcus aureus | gene expression analysis shows that pepZ expression is highest in the intracellular environment | up |
General Information
| General Information | Comment | Organism |
|---|---|---|
| malfunction | disruption of the pepZ gene results in an attenuation of virulence in both localized and systemic models of infection | Staphylococcus aureus |
| physiological function | LAP is required for survival inside human macrophages | Staphylococcus aureus |
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