Inhibitors | Comment | Organism | Structure |
---|---|---|---|
10-hydroxystearamide | - |
Homo sapiens | |
3-(decylthio)-1,1,1-trifluoropropan-2-one | moderate inhibition | Homo sapiens | |
3-(dodecylthio)-1,1,1-trifluoropropan-2-one | moderate inhibition | Homo sapiens | |
3-(octylthio)-1,1,1-trifluoropropan-2-one | moderate inhibition | Homo sapiens | |
methoxyarachidonyl fluorophosphate | - |
Homo sapiens |
KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
0.042 | - |
2-arachidonoylglycerol | at pH 7.4 and 37°C | Homo sapiens |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
microsome | - |
Homo sapiens | - |
- |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
cis-stilbene oxide + H2O | Homo sapiens | - |
(+)-(1R,2R)-1,2-diphenylethane-1,2-diol | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
Hep-G2 cell | - |
Homo sapiens | - |
LNCaP cell | - |
Homo sapiens | - |
PC-3 cell | - |
Homo sapiens | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
2-arachidonoylglycerol + H2O | - |
Homo sapiens | arachidonic acid + glycerol | - |
? | |
cis-stilbene oxide + H2O | - |
Homo sapiens | (+)-(1R,2R)-1,2-diphenylethane-1,2-diol | - |
? | |
additional information | no activity with 14,15-epoxyexicosatrienoic acid | Homo sapiens | ? | - |
? |
Synonyms | Comment | Organism |
---|---|---|
EPHX1 | - |
Homo sapiens |
IC50 Value | IC50 Value Maximum | Comment | Organism | Inhibitor | Structure |
---|---|---|---|---|---|
0.0000079 | - |
at pH 7.4 and 37°C | Homo sapiens | methoxyarachidonyl fluorophosphate |
General Information | Comment | Organism |
---|---|---|
metabolism | the enzyme plays a role in the endocannabinoid signaling and a new arachidonic acid biosynthetic pathway | Homo sapiens |