Literature summary for 3.3.2.9 extracted from

Lin, T.S.; Huang, H.H.; Fan, Y.H.; Chiou, S.H.; Chow, K.C.
Genetic polymorphism and gene expression of microsomal epoxide hydrolase in non-small cell lung cancer (2007), Oncol. Rep., 17, 565-572.

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Application

Application	Comment	Organism
medicine	investigation on the expression and genetic polymorphism of microsomal epoxide hydrolase in non-small cell lung cancer patients. Enzyme is expressed in 83% of biopsies analyzed, and the major allelic expression pattern is fast type (Tyr113) in exon 3 (90.3%) and slow type (His139) in exon 4 (100%). A significant difference in patient survival is found when enzyme expression and adriamycin-containing chemotherapy are used to group patients. With respect to cancer risk and disease progression, the expression level of enzyme seems as important as genetic polymorphism	Homo sapiens

Organism

Organism	UniProt	Comment	Textmining
Homo sapiens	P07099	non-small cell lung cancer patients	-

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Release 2023.1 (January 2023)