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Literature summary for 3.3.2.9 extracted from

  • Lin, Y.C.; Wu D.C.; Lee, J.M.; Hsu, H.K.; Kao, E.L.; Yang, C.H.; Wu, M.T.
    The association between microsomal epoxide hydrolase genotypes and esophageal sqamous-cell-carcinoma in Taiwan: interaction between areca chewing and smoking (2006), Cancer Lett., 237, 281-288.
    View publication on PubMed

Cloned(Commentary)

Cloned (Comment) Organism
genotyping of 497 humans Homo sapiens

Protein Variants

Protein Variants Comment Organism
H139R natural genotype, frequency of the polymorphism, the mutant enzyme shows increased activity compared to the wild-type enzyme Homo sapiens
additional information genotyping of 497 humans, enzyme polymorphisms are associated with esophageal squamous-cell-carcinoma, ESCC, and smoking or areca chewing, higher enzyme activity can contribute to lower the risk of cancer development, overview Homo sapiens
Y113H natural genotype, frequency of the polymorphism, the mutant enzyme shows reduced activity compared to the wild-type enzyme Homo sapiens

Localization

Localization Comment Organism GeneOntology No. Textmining
microsome
-
Homo sapiens
-
-

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining

Synonyms

Synonyms Comment Organism
mEH
-
Homo sapiens