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Literature summary for 3.3.2.9 extracted from

  • Watabe, T.; Ozawa, N.; Ishii, H.; Chiba, K.; Hiratsuka, A.
    Hepatic microsomal cholesterol epoxide hydrolase: selective inhibition by detergents and separation from xenobiotic epoxide hydrolase (1986), Biochem. Biophys. Res. Commun., 140, 632-637.
    View publication on PubMed
Search for more literature for 3.3.2.9

Activating Compound

Activating Compound Comment Organism Structure
Emulgen 108 2fold activation Mus musculus
Lubrol Px 2fold activation Mus musculus
sodium cholate slight activation Mus musculus
Triton WR-1339 nearly 2fold activation Mus musculus
Tween 80 slight activation Mus musculus

Inhibitors

Inhibitors Comment Organism Structure
Emulgen 911 slight inhibition Mus musculus

Localization

Localization Comment Organism GeneOntology No. Textmining
microsome
-
 Mus musculus
-
-

Organism

Organism UniProt Comment Textmining
Mus musculus
-
-
-

Purification (Commentary)

Purification (Comment) Organism
partially from liver by micosome preparation, two steps of gel filtration, separation from the cholesterol epoxide hydrolase, EC 3.3.2.11 Mus musculus

Source Tissue

Source Tissue Comment Organism Textmining
liver
-
 Mus musculus
-

Specific Activity [micromol/min/mg]

Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
0.0064
-
 liver microsomes Mus musculus

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
7-glycidoxycoumarin + H2O substrate is a stable epoxide Mus musculus 7-(1',2'-dihydroxy-3'-propoxy)coumarin
-
 ?

Synonyms

Synonyms Comment Organism
XEHase
-
 Mus musculus
xenobiotic epoxide hydrolase
-
 Mus musculus

Temperature Optimum [°C]

Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
37
-
 assay at Mus musculus

pH Optimum

pH Optimum Minimum pH Optimum Maximum Comment Organism
7.4
-
 assay at Mus musculus