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Literature summary for 3.3.2.9 extracted from
- Purification and characterization of dog liver microsomal epoxide hydrolase (1994), J. Biochem., 115, 985-990.
Activating Compound
| Activating Compound | Comment | Organism | Structure |
|---|---|---|---|
| Isoquinoline | stimulates | Canis lupus familiaris |  |
| Metyrapone | stimulates | Canis lupus familiaris | |
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| 1,1,1-Trichloropropene 2,3-oxide | - |
Canis lupus familiaris | |
| 2-Bromo-4'-nitroacetophenone | - |
Canis lupus familiaris | |
| Cyclohexene oxide | - |
Canis lupus familiaris | |
KM Value [mM]
| KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
|---|---|---|---|---|---|
| 0.17 | - |
7-glycidoxycoumarin | - |
Canis lupus familiaris | |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Canis lupus familiaris | - |
- |
- |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|
Specific Activity [micromol/min/mg]
| Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
|---|---|---|---|
| 1.98 | - |
- |
Canis lupus familiaris |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| 7-glycidoxycoumarin + H2O | - |
Canis lupus familiaris | ? | - |
? | |
pH Optimum
| pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
|---|---|---|---|
| 8 | - |
- |
Canis lupus familiaris |
pH Range
| pH Minimum | pH Maximum | Comment | Organism |
|---|---|---|---|
| 7 | 10 | pH 7.0: about 60% of maximal activity, pH 10.0: about 25% of maximal activity | Canis lupus familiaris |
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