Literature summary for 3.2.2.27 extracted from

Sartori, A.A.; Sch�r, P.; Fitz-Gibbon, S.; Miller, J.H.; Jiricny, J.
Biochemical characterization of uracil processing activities in the hyperthermophilic archaeon Pyrobaculum aerophilum (2001), J. Biol. Chem., 276, 29979-29986.

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Cloned(Commentary)

Cloned (Comment)	Organism
-	Pyrobaculum aerophilum

Molecular Weight [Da]

Molecular Weight [Da]	Molecular Weight Maximum [Da]	Comment	Organism
25000	-	x * 25000, SDS-PAGE	Pyrobaculum aerophilum

Organism

Organism	UniProt	Comment	Textmining
Pyrobaculum aerophilum	Q8ZYS2	-	-
Pyrobaculum aerophilum DSM 7523	Q8ZYS2	-	-

Purification (Commentary)

Purification (Comment)	Organism
-	Pyrobaculum aerophilum

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
uracil-mismatched double-stranded DNA + H2O	uracil residues in G/U mispairs, in A/U pairs. Preference for G/U substrate over A/U substrate and uracil in single-stranded DNA	Pyrobaculum aerophilum	uracil + double-stranded DNA with abasic site	-	?
uracil-mismatched double-stranded DNA + H2O	uracil residues in G/U mispairs, in A/U pairs. Preference for G/U substrate over A/U substrate and uracil in single-stranded DNA	Pyrobaculum aerophilum DSM 7523	uracil + double-stranded DNA with abasic site	-	?
uracil-mismatched single-stranded DNA + H2O	-	Pyrobaculum aerophilum	uracil + single-stranded DNA with abasic site	-	?
uracil-mismatched single-stranded DNA + H2O	-	Pyrobaculum aerophilum DSM 7523	uracil + single-stranded DNA with abasic site	-	?

Subunits

Subunits	Comment	Organism
?	x * 25000, SDS-PAGE	Pyrobaculum aerophilum

Synonyms

Synonyms	Comment	Organism
Pa-UDG	-	Pyrobaculum aerophilum

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Release 2023.1 (January 2023)