Literature summary for 3.2.2.27 extracted from

Huang, H.; Stivers, J.T.; Greenberg, M.M.
Competitive inhibition of uracil DNA glycosylase by a modified nucleotide whose triphosphate is a substrate for DNA polymerase (2009), J. Am. Chem. Soc., 131, 1344-1345.

Search for more literature for 3.2.2.27

Inhibitors

Inhibitors	Comment	Organism	Structure
1'-cyano-2'-deoxyuridine	-	Escherichia coli
1'-cyano-2'-deoxyuridine	-	Homo sapiens
DNA containing 1'-cyano-2'-deoxyuridine	CNdU, a UDG inhibitor whose respective nucleotide triphosphate is also a substrate for DNA polymerase	Escherichia coli
DNA containing 1'-cyano-2'-deoxyuridine	CNdU, a UDG inhibitor whose respective nucleotide triphosphate is also a substrate for DNA polymerase	Homo sapiens

Organism

Organism	UniProt	Comment	Textmining
Escherichia coli	-	-	-
Homo sapiens	P13051	-	-

Synonyms

Synonyms	Comment	Organism
UDG	-	Escherichia coli
UDG	-	Homo sapiens
uracil DNA glycosylase	-	Escherichia coli
uracil DNA glycosylase	-	Homo sapiens

Ki Value [mM]

Ki Value [mM]	Ki Value maximum [mM]	Inhibitor	Comment	Organism	Structure
0.0046	-	1'-cyano-2'-deoxyuridine	-	Escherichia coli
0.0138	-	1'-cyano-2'-deoxyuridine	-	Homo sapiens
0.1315	-	DNA containing 1'-cyano-2'-deoxyuridine	-	Homo sapiens
0.2457	-	DNA containing 1'-cyano-2'-deoxyuridine	-	Escherichia coli

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Release 2023.1 (January 2023)