Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary for 3.2.2.23 extracted from

  • Ondovcik, S.L.; Preston, T.J.; McCallum, G.P.; Wells, P.G.
    Expression of human oxoguanine glycosylase 1 or formamidopyrimidine glycosylase in human embryonic kidney 293 cells exacerbates methylmercury toxicity in vitro (2013), Toxicol. Appl. Pharmacol., 271, 41-48.
    View publication on PubMed
Search for more literature for 3.2.2.23

Cloned(Commentary)

Cloned (Comment) Organism
expressed in HEK-293 cells Homo sapiens

Localization

Localization Comment Organism GeneOntology No. Textmining
mitochondrion
-
 Homo sapiens 5739
-

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
30000
-
 x * 30000, SDS-PAGE Homo sapiens

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
DNA containing 8-oxo-2'-deoxyguanosine residues + H2O Homo sapiens
-
 DNA + 8-oxo-2'-deoxyguanosine
-
 ?

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
DNA containing 8-oxo-2'-deoxyguanosine residues + H2O
-
 Homo sapiens DNA + 8-oxo-2'-deoxyguanosine
-
 ?

Subunits

Subunits Comment Organism
? x * 30000, SDS-PAGE Homo sapiens

Synonyms

Synonyms Comment Organism
formamidopyrimidine glycosylase
-
 Homo sapiens
FPG
-
 Homo sapiens

General Information

General Information Comment Organism
physiological function Fpg-expressing cells show increased susceptibility to methylmercury-initiated cytotoxicity Homo sapiens