Cloned (Comment) | Organism |
---|---|
gene Rv2924c encoding Mtb-Fpg1, DNA and amino acid sequence determination and analysis, relationship between tandem repeat length and Mtb-fpg1 expression levels, quantitative expression analysis, overview | Mycobacterium tuberculosis |
Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|
31950 | - |
x * 31950, Mtb-Fpg1, sequence calculation, x * 32000, recombinant Mtb-Fpg1, SDS-PAGE | Mycobacterium tuberculosis |
32000 | - |
x * 31950, Mtb-Fpg1, sequence calculation, x * 32000, recombinant Mtb-Fpg1, SDS-PAGE | Mycobacterium tuberculosis |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Mycobacterium tuberculosis | P9WNC3 | - |
- |
Mycobacterium tuberculosis | P9WNC3 | gene Rv2924c | - |
Mycobacterium tuberculosis H37Rv | P9WNC3 | - |
- |
Mycobacterium tuberculosis H37Rv | P9WNC3 | gene Rv2924c | - |
Purification (Comment) | Organism |
---|---|
recombinant Mtb-Fpg1 to homogeneity | Mycobacterium tuberculosis |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
additional information | molecular strain typing, and enzyme expression level, overview | Mycobacterium tuberculosis | - |
additional information | molecular strain typing, and enzyme expression levels in strain H37Rv and other isolates, overview | Mycobacterium tuberculosis | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
additional information | Mtb-Fpg1 removes formamidopyrimidine and 5-hydroxycytosine lesions, as well as 8-oxo-7,8-dihydroguanine opposite to C, T and G. Substrates are duplex DNA substrates containing a single 8oxoG opposite of C, A, G, T, 5-hydroxycytosine (5OHC):G, 5-hydroxyuracil (5OHU):G, DHU:G, U:A or U:G base pair | Mycobacterium tuberculosis | ? | - |
? | |
additional information | Mtb-Fpg1 removes formamidopyrimidine and 5-hydroxycytosine lesions, as well as 8-oxo-7,8-dihydroguanine opposite to C, T and G. Substrates are duplex DNA substrates containing a single 8oxoG opposite of C, A, G, T, 5-hydroxycytosine (5OHC):G, 5-hydroxyuracil (5OHU):G, DHU:G, U:A or U:G base pair | Mycobacterium tuberculosis H37Rv | ? | - |
? |
Subunits | Comment | Organism |
---|---|---|
? | x * 31950, Mtb-Fpg1, sequence calculation, x * 32000, recombinant Mtb-Fpg1, SDS-PAGE | Mycobacterium tuberculosis |
Synonyms | Comment | Organism |
---|---|---|
Fapy-DNA glycosylase | - |
Mycobacterium tuberculosis |
formamidopyrimidine-DNA glycosylase | - |
Mycobacterium tuberculosis |
FPG | - |
Mycobacterium tuberculosis |
Mtb-Fpg1 | - |
Mycobacterium tuberculosis |