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Literature summary for 3.2.2.23 extracted from

  • Jain, R.; Kumar, P.; Varshney, U.
    A distinct role of formamidopyrimidine DNA glycosylase (MutM) in down-regulation of accumulation of G, C mutations and protection against oxidative stress in mycobacteria (2007), DNA Repair, 6, 1774-1785.
    View publication on PubMed

Protein Variants

Protein Variants Comment Organism
additional information gene disruption mutants exhibits an enhanced mutator phenotype and susceptibility to hydrogen peroxide as well as a remarkable increase in accumulation of A to G (or T to C) mutations. Exposure of the mutant to sub-lethal level of hydrogen peroxide results in a major shift toward C to G (or G to C) mutations Mycolicibacterium smegmatis

Organism

Organism UniProt Comment Textmining
Mycolicibacterium smegmatis
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