Crystallization (Comment) | Organism |
---|---|
crystal structure of enzyme bound to a 1,3-propanediol abasic site analogue-containing DNA | Lactococcus lactis |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
DNA + H2O | Lactococcus lactis | removes oxidized purines from oxidatively damaged DNA | ? | - |
? | |
DNA + H2O | Lactococcus lactis | bifunctional base excision repair enzyme: DNA glycosylase/AP lyase | ? | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Lactococcus lactis | - |
- |
- |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
DNA + H2O | removes a wide range of oxidized purines, such as 8-oxoguanine and imidazole ring-opened purines, from oxidatively damaged DNA, DNA glycosylase/AP lyase activity, substrate recognition | Lactococcus lactis | ? | - |
? | |
DNA + H2O | removes oxidized purines from oxidatively damaged DNA | Lactococcus lactis | ? | - |
? | |
DNA + H2O | enzyme has N-glycosylase and apurinic/apyrimidinic lyase activity | Lactococcus lactis | ? | - |
? | |
DNA + H2O | bifunctional base excision repair enzyme: DNA glycosylase/AP lyase | Lactococcus lactis | ? | - |
? | |
DNA containing 7-hydro-8-oxoguanine residues + H2O | removes 8-oxoguanine from oxidatively damaged DNA | Lactococcus lactis | DNA + 7-hydro-8-oxoguanine | - |
? | |
DNA containing 7-hydro-8-oxoguanine residues + H2O | DNA glycosylase/AP lyase activity | Lactococcus lactis | DNA + 7-hydro-8-oxoguanine | - |
? |