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Literature summary for 3.2.2.22 extracted from

  • Raimo, G.; Arcucci, A.; Barbieri, L.; Valbonesi, P.; Masullo, M.; Stirpe, F.; Bocchini, V.
    The effect of ribosome-inactivating proteins on the ribosome from the hyperthermophilic archaeon Sulfolobus solfataricus (1998), Biochem. Mol. Biol. Int., 44, 665-672.
    View publication on PubMed
Search for more literature for 3.2.2.22

Localization

Localization Comment Organism GeneOntology No. Textmining

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
adenosine in rRNA + H2O Saccharolobus solfataricus rRNA is depurinated thus producing inactive ribosomes and inhibition protein synthesis probably due to the lack of the interaction between depurinated ribosomes and elongation factor 2 deadenylated rRNA + adenine
-
 ?

Organism

Organism UniProt Comment Textmining
Saccharolobus solfataricus
-
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
adenosine in rRNA + H2O
-
 Saccharolobus solfataricus deadenylated rRNA + adenine
-
 ?
adenosine in rRNA + H2O rRNA is depurinated thus producing inactive ribosomes and inhibition protein synthesis probably due to the lack of the interaction between depurinated ribosomes and elongation factor 2 Saccharolobus solfataricus deadenylated rRNA + adenine
-
 ?

Synonyms

Synonyms Comment Organism
polynucleotide:adenosine glycosylase
-
 Saccharolobus solfataricus
RIP
-
 Saccharolobus solfataricus
type 1 ribosome-inactivating protein
-
 Saccharolobus solfataricus

Temperature Optimum [°C]

Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
25
-
 assay at Saccharolobus solfataricus

pH Optimum

pH Optimum Minimum pH Optimum Maximum Comment Organism
7.8
-
 assay at Saccharolobus solfataricus

General Information

General Information Comment Organism
physiological function rRNA is depurinated thus producing inactive ribosomes and inhibition protein synthesis Saccharolobus solfataricus