Application | Comment | Organism |
---|---|---|
medicine | ricin stimulates human monocyte/macrophage cell line 28SC to secrete interleukin IL-8. IL-8 induction can be blocked by brefeldin A. After ricin exposure, p38 mitogen activated protein kinase levels are elevated. Treatment of cells with p38 mitogen activated protein kinase inhibitor SB203580 suppresses ricin-mediated IL-8 release | Ricinus communis |
Organism | UniProt | Comment | Textmining |
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Ricinus communis | - |
- |
- |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
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additional information | ricin stimulates human monocyte/macrophage cell line 28SC to secrete interleukin IL-8. IL-8 induction can be blocked by brefeldin A. After ricin exposure, p38 mitogen activated protein kinase levels are elevated. Treatment of cells with p38 mitogen activated protein kinase inhibitor SB203580 suppresses ricin-mediated IL-8 release | Ricinus communis | ? | - |
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