Literature summary for 3.2.2.22 extracted from

Jolliffe, N.A.; Di Cola, A.; Marsden, C.J.; Lord, J.M.; Ceriotti, A.; Frigerio, L.; Roberts, L.M.
The N-terminal ricin propeptide influences the fate of ricin A-chain in tobacco protoplasts (2006), J. Biol. Chem., 281, 23377-23385.

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Localization

Localization	Comment	Organism	GeneOntology No.	Textmining

Organism

Organism	UniProt	Comment	Textmining
Ricinus communis	-	-	-

Posttranslational Modification

Posttranslational Modification	Comment	Organism
proteolytic modification	removal of the signal peptide of ricin precursor generates proricin in which the mature A- and B-chains are joined by an intervening propeptide and a 9-residue propeptide persists at the N terminus. The N-terminal propeptide of proricin acts as a nonspecific spacer to ensure efficient ER import and glycosylation. The propeptide does not influence catalytic activity per se or the vacuolar targeting of proricin or the rate of retrotranslocation/degradation of A-chain in the cytosol	Ricinus communis

Source Tissue

Source Tissue	Comment	Organism	Textmining

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Release 2023.1 (January 2023)