Literature summary for 3.2.2.22 extracted from

Ye, W.; Nanga, R.P.; Kang, C.B.; Song, J.H.; Song, S.K.; Yoon, H.S.
Molecular characterization of the recombinant A-chain of a type II ribosome-inactivating protein (RIP) from Viscum album coloratum and structural basis on its ribosome-inactivating activity and the sugar-binding properties of the B-chain (2006), J. Biochem. Mol. Biol., 39, 560-570.

Search for more literature for 3.2.2.22

Cloned(Commentary)

Cloned (Comment)	Organism
expression of both the A and the B chains of KML separately in a bacterial expression system	Viscum album

Crystallization (Commentary)

Crystallization (Comment)	Organism
homology modeling of both A and B chain protein and comparison with European mistletoe lectin-1, Himalayan mistletoe lectin, and ricin	Viscum album

Organism

Organism	UniProt	Comment	Textmining
Viscum album	-	coloratum, type II ribosome inactivating protein	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
additional information	in vitro synthesis of luciferase in a rabbit reticulocyte lysate system is inhibited by enzyme A chain protein. Enzyme A chain as well as native enzyme inhibits the growth of MCF7/caspases-3 (+) cells. Key catalytic residues are Tyr76, Tyr115, Glu165, and Arg168	Viscum album	?	-	?

Synonyms

Synonyms	Comment	Organism
KML	-	Viscum album

Use of this online version of BRENDA is free under the CC BY 4.0 license. See terms of use for full details.

Release 2023.1 (January 2023)