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Literature summary for 3.2.2.22 extracted from
- Effect of surface charge and density of distearylphosphatidylethanolamine-mPEG-2000 (DSPE-mPEG-2000) on the cytotoxicity of liposome-entrapped ricin: effect of lysosomotropic agents (2008), Int. J. Pharm., 350, 79-94.
Application
| Application | Comment | Organism |
|---|---|---|
| medicine | study on the cytotoxicity of ricin encapsulated in various liposomes. Cytotoxicity against CHO pro- cells is significnatly dependent on the charge on the surface of liposomes. Maximum cytotoxicity is observed by delivering ricin through negatively charged liposomes. Monensin enhances the cytotoxicity with maximum potentiation on delivery through positively charged liposomes and depending on the density of distearylphosphatidylethanolamine-mPEG-2000 on their surface | Ricinus communis |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Ricinus communis | - |
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